Alcohol consumption and diabetes risk in the Diabetes Prevention Program.

ABSTRACT:

Background

Moderate alcohol consumption is associated with a decreased risk of type 2 diabetes in the general population, but little is known about the effects in individuals at high risk of diabetes.

Objectives

The objectives were to determine associations between alcohol consumption and diabetes risk factors and whether alcohol consumption was a predictor of incident diabetes in individuals enrolled in the Diabetes Prevention Program (DPP).

Design

DPP participants (n = 3175) had impaired glucose tolerance (2-h glucose: 7.8-11.1 mmol/L), elevated fasting glucose (5.3-7.0 mmol/L), and a body mass index (in kg/m(2)) > or =24. Participants were randomly assigned to placebo, metformin, or lifestyle modification and were followed for a mean of 3.2 y. Alcohol intake was as

SUBMITTER: Crandall JP 

PROVIDER: S-EPMC2728644 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature