Coherent X-ray diffraction from collagenous soft tissues.

ABSTRACT: Coherent X-ray diffraction has been applied in the imaging of inorganic materials with great success. However, its application to biological specimens has been limited to some notable exceptions, due to the induced radiation damage and the extended nature of biological samples, the last limiting the application of most part of the phasing algorithms. X-ray ptychography, still under development, is a good candidate to overcome such difficulties and become a powerful imaging method for biology. We describe herein the feasibility of applying ptychography to the imaging of biological specimens, in particular collagen rich samples. We report here speckles in diffraction patterns from soft animal tissue, obtained with an optimized small angle X-ray setup that exploits the natural coherence of th

SUBMITTER: Berenguer de la Cuesta F 

PROVIDER: S-EPMC2730963 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature