The FunGenES database: a genomics resource for mouse embryonic stem cell differentiation.

ABSTRACT: Embryonic stem (ES) cells have high self-renewal capacity and the potential to differentiate into a large variety of cell types. To investigate gene networks operating in pluripotent ES cells and their derivatives, the "Functional Genomics in Embryonic Stem Cells" consortium (FunGenES) has analyzed the transcriptome of mouse ES cells in eleven diverse settings representing sixty-seven experimental conditions. To better illustrate gene expression profiles in mouse ES cells, we have organized the results in an interactive database with a number of features and tools. Specifically, we have generated clusters of transcripts that behave the same way under the entire spectrum of the sixty-seven experimental conditions; we have assembled genes in groups according to their time of expression durin

SUBMITTER: Schulz H 

PROVIDER: S-EPMC2731164 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature