Cost-effectiveness of total knee arthroplasty in the United States: patient risk and hospital volume.

ABSTRACT:

Background

Total knee arthroplasty (TKA) relieves pain and improves quality of life for persons with advanced knee osteoarthritis. However, to our knowledge, the cost-effectiveness of TKA and the influences of hospital volume and patient risk on TKA cost-effectiveness have not been investigated in the United States.

Methods

We developed a Markov, state-transition, computer simulation model and populated it with Medicare claims data and cost and outcomes data from national and multinational sources. We projected lifetime costs and quality-adjusted life expectancy (QALE) for different risk populations and varied TKA intervention and hospital volume. Cost-effectiveness of TKA was estimated across all patient risk and hospital volume permutations. Finally, we conducted sensitivi

SUBMITTER: Losina E 

PROVIDER: S-EPMC2731300 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature