Ontology highlight
ABSTRACT:
SUBMITTER: Jeha S
PROVIDER: S-EPMC2731684 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
Leukemia 20090312 8
To evaluate the impact of contemporary therapy on the clinical outcome of children with pre-B acute lymphoblastic leukemia (ALL) and the t(1;19)/TCF3/PBX1, we analyzed 735 patients with B-cell precursor ALL treated in four successive protocols at St Jude Children's Research Hospital. The 41 patients with the t(1;19) had a comparable event-free survival to that of the 694 patients with other B-cell precursor ALL (P=0.63; 84.2+/-7.1% (s.e.) vs 84.0+/-1.8% at 5 years). However, patients with the t( ...[more]