Association between serum uric acid and development of type 2 diabetes.

ABSTRACT:

Objective

To systematically evaluate the association between serum uric acid (SUA) level and subsequent development of type 2 diabetes.

Research design and methods

We searched Medline (31 March from 1966 to 2009) and Embase (31 March from 1980 to 2009) for observational cohort studies examining the association between SUA and the risk of type 2 diabetes by manual literature search. Relative risks (RRs) for each 1 mg/dl increase in SUA were pooled by using a random-effects model. The studies included were stratified into subgroups representing different study characteristics, and meta-regression analyses were performed to investigate the effect of these characteristics on the association between SUA level and type 2 diabetes risk.

Results

The search yielded 11 cohort s

SUBMITTER: Kodama S 

PROVIDER: S-EPMC2732137 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature