Positive association between Helicobacter pylori and gastroesophageal reflux disease in children.

ABSTRACT:

Objectives

The role of Helicobacter pylori (H pylori) in gastroesophageal reflux disease (GERD) remains controversial, particularly in children, because there are limited published data. Adult studies suggested that H pylori infection may protect against GERD by causing atrophic gastritis, which leads to reduced gastric acid secretion. The objective of our study was to determine the role of H pylori infection in the development of GERD in a pediatric population.

Patients and methods

A retrospective analysis of 420 patients (M:F = 214:206) who underwent esophagogastroduodenoscopy (EGD) with biopsies between January 2000 and April 2006 was conducted. Patient demographics, clinical indications for EGD and the prevalence of reflux esophagitis (RE), the biomarker for GERD, in 2 g

SUBMITTER: Moon A 

PROVIDER: S-EPMC2732756 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature