Change in cartilage morphometry: a sample of the progression cohort of the Osteoarthritis Initiative.

ABSTRACT:

Objective

The performance characteristics of hyaline articular cartilage measurement on magnetic resonance imaging (MRI) need to be accurately delineated before widespread application of this technology. Our objective was to assess the rate of natural disease progression of cartilage morphometry measures from baseline to 1 year in knees with osteoarthritis (OA) from a subset of participants from the Osteoarthritis Initiative (OAI).

Methods

Subjects included for this exploratory analysis are a subset of the approximately 4700 participants in the OAI Study. Bilateral radiographs and 3T MRI (Siemans Trio) of the knees and clinical data were obtained at baseline and annually in all participants. 160 subjects from the OAI Progression subcohort all of whom had both frequent sympto

SUBMITTER: Hunter DJ 

PROVIDER: S-EPMC2734969 | biostudies-literature | 2009 Mar

REPOSITORIES: biostudies-literature