Ontology highlight
ABSTRACT:
SUBMITTER: Mavrich TN
PROVIDER: S-EPMC2735122 | biostudies-literature | 2008 May
REPOSITORIES: biostudies-literature
Nature 20080413 7193
Comparative genomics of nucleosome positions provides a powerful means for understanding how the organization of chromatin and the transcription machinery co-evolve. Here we produce a high-resolution reference map of H2A.Z and bulk nucleosome locations across the genome of the fly Drosophila melanogaster and compare it to that from the yeast Saccharomyces cerevisiae. Like Saccharomyces, Drosophila nucleosomes are organized around active transcription start sites in a canonical -1, nucleosome-fre ...[more]