Synthesis and microcontact printing of dual end-functionalized mucin-like glycopolymers for microarray applications.

ABSTRACT: Click to view: Glycopolymers can be used to display glycans on microarrays in native-like architectures. The structurally uniform alkyne-terminated mucin mimetic glycopolymers (see picture; TR = fluorophore) were printed on azide-functionalized chips by microcontact printing in the presence of a copper catalyst. The surface-bound glycopolymers bind lectins in a ligand-specific manner.

SUBMITTER: Godula K 

PROVIDER: S-EPMC2735190 | biostudies-literature | 2009

REPOSITORIES: biostudies-literature