Human papilloma virus is associated with breast cancer.

ABSTRACT:

Background

There is increasing evidence that high-risk human papilloma virus (HPV) is involved in cancers in addition to cervical cancer. For example, it is generally accepted that HPV has a role in a significant proportion of head and neck tumours, and it has long been hypothesised that hormone dependent oncogenic viruses, such as HPV may have causal roles in some human breast cancers. A number of reports have identified HPV DNA in breast tissue and breast cancer specimens, but these rely on standard polymerase chain reaction (PCR), which is criticised for its propensity for contamination.

Methods

We have used two different technologies, in situ and standard PCR (with sequencing), and histology based on light microscopy.

Results

We unambiguously demonstrate the prese

SUBMITTER: Heng B 

PROVIDER: S-EPMC2737128 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature