D-MATRIX: a web tool for constructing weight matrix of conserved DNA motifs.

ABSTRACT:

Unlabelled

Despite considerable efforts to date, DNA motif prediction in whole genome remains a challenge for researchers. Currently the genome wide motif prediction tools required either direct pattern sequence (for single motif) or weight matrix (for multiple motifs). Although there are known motif pattern databases and tools for genome level prediction but no tool for weight matrix construction. Considering this, we developed a D-MATRIX tool which predicts the different types of weight matrix based on user defined aligned motif sequence set and motif width. For retrieval of known motif sequences user can access the commonly used databases such as TFD, RegulonDB, DBTBS, Transfac. D-MATRIX program uses a simple statistical approach for weight matrix construction, which can be conv

SUBMITTER: Sen N 

PROVIDER: S-EPMC2737498 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature