Prevention of depression in at-risk adolescents: a randomized controlled trial.

ABSTRACT:

Context

Adolescent offspring of depressed parents are at markedly increased risk of developing depressive disorders. Although some smaller targeted prevention trials have found that depression risk can be reduced, these results have yet to be replicated and extended to large-scale, at-risk populations in different settings.

Objective

To determine the effects of a group cognitive behavioral (CB) prevention program compared with usual care in preventing the onset of depression.

Design, setting, and participants

A multicenter randomized controlled trial conducted in 4 US cities in which 316 adolescent (aged 13-17 years) offspring of parents with current or prior depressive disorders were recruited from August 2003 through February 2006. Adolescents had a past history of

SUBMITTER: Garber J 

PROVIDER: S-EPMC2737625 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature