Neurologic abnormalities in HTLV-I- and HTLV-II-infected individuals without overt myelopathy.

ABSTRACT:

Background

Human T-lymphotropic virus (HTLV) type I is the causative agent of HTLV-associated myelopathy (HAM)/tropical spastic paraparesis, and a number of HAM cases with HTLV-II infection have also been reported. However, despite some reports, it is unclear whether HTLV-I or -II infection is associated with other neurologic manifestations.

Methods

An analysis of medical histories and screening neurologic examinations from a prospective cohort of 153 HTLV-I, 388 HTLV-II, and 810 HTLV-seronegative individuals followed up for means of 11.5, 12.0, and 12.2 years was performed. Participants diagnosed with HAM were excluded. We calculated odds ratios (ORs) and 95% confidence intervals (CIs), adjusting for age, sex, race or ethnicity, income, educational attainment, body mass ind

SUBMITTER: Biswas HH 

PROVIDER: S-EPMC2739606 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature