Corallolides A and B: bioactive diterpenes featuring a novel carbon skeleton.

ABSTRACT: Corallolides A (1) and B (2) are naturally occurring diterpenes isolated from the Caribbean gorgonian octocoral Pseudopterogorgia bipinnata collected near Providencia Island, Colombia. Their tricyclic structures are based on a uniquely substituted bicyclo[9.2.1]tetradecane ring system that was established through detailed spectroscopic analysis. Compounds 1 and 2 were shown to exhibit antiparasitic and antituberculosis activity, respectively.

SUBMITTER: Ospina CA 

PROVIDER: S-EPMC2740495 | biostudies-literature | 2009 Aug

REPOSITORIES: biostudies-literature