Ontology highlight
ABSTRACT:
SUBMITTER: Yun NE
PROVIDER: S-EPMC2741389 | biostudies-literature | 2009 Jun
REPOSITORIES: biostudies-literature
Vaccine 20090503 30
Studying the mechanisms of host survival resulting from viral encephalitis is critical to the development of vaccines. Here we have shown in several independent studies that high dose treatment with neutralizing antibody prior to intranasal infection with Venezuelan equine encephalitis virus had an antiviral effect in the visceral organs and prolonged survival time of infected mice, even in the absence of alphabeta T cells. Nevertheless, antibody treatment did not prevent the development of leth ...[more]