An integrated genetic linkage map for silkworms with three parental combinations and its application to the mapping of single genes and QTL.

ABSTRACT:

Background

Bombyx mori, the domesticated silkworm, is a well-studied model insect with great economic and scientific significance. Although more than 400 mutations have been described in silkworms, most have not been identified, especially those affecting economically-important traits. Simple sequence repeats (SSRs) are effective and economical tools for mapping traits and genetic improvement. The current SSR linkage map is of low density and contains few polymorphisms. The purpose of this work was to develop a dense and informative linkage map that would assist in the preliminary mapping and dissection of quantitative trait loci (QTL) in a variety of silkworm strains.

Results

Through an analysis of > 50,000 genotypes across new mapping populations, we constructed two new li

SUBMITTER: Zhan S 

PROVIDER: S-EPMC2741490 | biostudies-literature | 2009 Aug

REPOSITORIES: biostudies-literature