Predictors of pregnancy in women with polycystic ovary syndrome.

ABSTRACT:

Context

Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility. The selection of first-line therapies for ovulation induction is empiric.

Objective

The aim of the study was to develop a clinically useful predictive model of live birth with varying ovulation induction methods.

Design, setting, and participants

We built four prognostic models from a large multicenter randomized controlled infertility trial of 626 women with PCOS performed at academic health centers in the United States to predict success of ovulation, conception, pregnancy, and live birth, evaluating the influence of patients' baseline characteristics.

Interventions

Ovulation was induced with clomiphene, metformin, or the combination of both for up to six cycles or c

SUBMITTER: Rausch ME 

PROVIDER: S-EPMC2741722 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature