Impact of the lung allocation score on lung transplantation for pulmonary arterial hypertension.

ABSTRACT:

Rationale

In 2005, lung allocation for transplantation in the United States changed from a system based on waiting time to a system based on the Lung Allocation Score (LAS).

Objectives

To study the effect of the LAS on lung transplantation for idiopathic pulmonary arterial hypertension (IPAH) compared with other major diagnoses.

Methods

We studied 7,952 adults listed for lung transplantation between 2002 and 2008. Analyses were restricted to patients with IPAH, idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD), and cystic fibrosis (CF). Transplantation, waiting list mortality, and post-transplant mortality were compared between diagnoses for patients listed before and after implementation of the LAS.

Measurements and main results

SUBMITTER: Chen H 

PROVIDER: S-EPMC2742763 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature