Brucella microti: the genome sequence of an emerging pathogen.

ABSTRACT:

Background

Using a combination of pyrosequencing and conventional Sanger sequencing, the complete genome sequence of the recently described novel Brucella species, Brucella microti, was determined. B. microti is a member of the genus Brucella within the Alphaproteobacteria, which consists of medically important highly pathogenic facultative intracellular bacteria. In contrast to all other Brucella species, B. microti is a fast growing and biochemically very active microorganism with a phenotype more similar to that of Ochrobactrum, a facultative human pathogen. The atypical phenotype of B. microti prompted us to look for genomic differences compared to other Brucella species and to look for similarities with Ochrobactrum.

Results

The genome is composed of two circular chromo

SUBMITTER: Audic S 

PROVIDER: S-EPMC2743711 | biostudies-literature | 2009 Aug

REPOSITORIES: biostudies-literature