Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study.

ABSTRACT:

Objective

To determine the relation between exposure to glycaemia over time and the risk of macrovascular or microvascular complications in patients with type 2 diabetes.

Design

Prospective observational study.

Setting

23 hospital based clinics in England, Scotland, and Northern Ireland.

Participants

4585 white, Asian Indian, and Afro-Caribbean UKPDS patients, whether randomised or not to treatment, were included in analyses of incidence; of these, 3642 were included in analyses of relative risk.

Outcome measures

Primary predefined aggregate clinical outcomes: any end point or deaths related to diabetes and all cause mortality. Secondary aggregate outcomes: myocardial infarction, stroke, amputation (including death from peripheral vascular disease), and

SUBMITTER: Stratton IM 

PROVIDER: S-EPMC27454 | biostudies-literature | 2000 Aug

REPOSITORIES: biostudies-literature