Comparative genomics of chondrichthyan Hoxa clusters.

ABSTRACT:

Background

The chondrichthyan or cartilaginous fish (chimeras, sharks, skates and rays) occupy an important phylogenetic position as the sister group to all other jawed vertebrates and as an early lineage to diverge from the vertebrate lineage following two whole genome duplication events in vertebrate evolution. There have been few comparative genomic analyses incorporating data from chondrichthyan fish and none comparing genomic information from within the group. We have sequenced the complete Hoxa cluster of the Little Skate (Leucoraja erinacea) and compared to the published Hoxa cluster of the Horn Shark (Heterodontus francisci) and to available data from the Elephant Shark (Callorhinchus milii) genome project.

Results

A BAC clone containing the full Little Skate Hoxa cl

SUBMITTER: Mulley JF 

PROVIDER: S-EPMC2746220 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature