Early arterial hypotension is common in the post-cardiac arrest syndrome and associated with increased in-hospital mortality.

ABSTRACT:

Aim

After return of spontaneous circulation (ROSC) from cardiac arrest, profound myocardial stunning and systemic inflammation may cause hemodynamic alterations; however, the prevalence of post-ROSC hemodynamic instability and the strength of association with outcome have not been established. We tested the hypothesis that exposure to arterial hypotension after ROSC occurs commonly (>50%) and is an independent predictor of death.

Methods

Single-center retrospective cohort study of all post-cardiac arrest patients over 1 year.

Inclusion criteria

(1) age >17; (2) non-trauma; (3) sustained ROSC after cardiac arrest. Using the Jones criteria, subjects were assigned to one of two groups based on the presence of hypotension within 6h after ROSC: (1) exposures-two or more sy

SUBMITTER: Kilgannon JH 

PROVIDER: S-EPMC2746417 | biostudies-literature | 2008 Dec

REPOSITORIES: biostudies-literature