Longitudinal study of new eye lesions in children with toxoplasmosis who were not treated during the first year of life.

ABSTRACT:

Purpose

To determine the incidence of new chorioretinal lesions in children with toxoplasmosis diagnosed after, and therefore not treated during, their first year.

Design

Prospective longitudinal cohort study.

Methods

Thirty-eight children were evaluated in Chicago between 1981 and 2005 for new chorioretinal lesions. Thirty-eight children and mothers had serum IgG antibody to Toxoplasma gondii.

Results

Twenty-eight of 38 children had one of the following: diagnosis with serum antibody to T. gondii indicative of chronic infection at age 24 months, central nervous system calcifications, hydrocephalus, illness compatible with congenital toxoplasmosis perinatally but not diagnosed at that time. Twenty-five returned for follow-up during 1981 to 2005. Their mean (ran

SUBMITTER: Phan L 

PROVIDER: S-EPMC2747816 | biostudies-literature | 2008 Sep

REPOSITORIES: biostudies-literature