GEM-TREND: a web tool for gene expression data mining toward relevant network discovery.

ABSTRACT:

Background

DNA microarray technology provides us with a first step toward the goal of uncovering gene functions on a genomic scale. In recent years, vast amounts of gene expression data have been collected, much of which are available in public databases, such as the Gene Expression Omnibus (GEO). To date, most researchers have been manually retrieving data from databases through web browsers using accession numbers (IDs) or keywords, but gene-expression patterns are not considered when retrieving such data. The Connectivity Map was recently introduced to compare gene expression data by introducing gene-expression signatures (represented by a set of genes with up- or down-regulated labels according to their biological states) and is available as a web tool for detecting similar gen

SUBMITTER: Feng C 

PROVIDER: S-EPMC2748096 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature