Expression of protocadherin-9 and protocadherin-17 in the nervous system of the embryonic zebrafish.

ABSTRACT: In this study we analyzed expression patterns of two delta-protocadherins, protocadherin-9 and protocadherin-17, in the developing zebrafish using in situ hybridization and RT-PCR methods. Both protocadherins were mainly detected in the embryonic central nervous system, but each showed a distinct expression pattern. Protocadherin-9 message (Pcdh9) was expressed after 10h post fertilization (hpf). It was found mainly in small clusters of cells in the anteroventral forebrain and ventrolateral hindbrain, and scattered cells throughout the spinal cord of young embryos (24 hpf). Pcdh9 expression in the hindbrain was segmental, reflecting a neuromeric organization, which became more evident at 34 hpf. As development proceeded, Pcdh9 expression increased throughout the brain, while its expression

SUBMITTER: Liu Q 

PROVIDER: S-EPMC2748168 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature