Palladium-catalyzed asymmetric dearomatization of naphthalene derivatives.

ABSTRACT: An intramolecular enantioselective metal-catalyzed dearomatization reaction is described. This procedure allows the dearomatization of naphthalene derivatives through an electrophilic aromatic substitution-type reaction on a Pd(II) intermediate. The high yields and enantioselectivities achieved make this procedure a valuable method for synthetic chemists.

SUBMITTER: Garcia-Fortanet J 

PROVIDER: S-EPMC2748791 | biostudies-literature | 2009 May

REPOSITORIES: biostudies-literature