Gene array analysis of adrenal glands in broiler chickens following ACTH treatment.

ABSTRACT:

Background

Difference in adaptability responses to stress has been observed amongst bird species, strains, and individuals. Components of the HPA axis, one of the internal systems involved in homeostasis re-establishment following stress, could play a role in this variability of responses. The aim of the present study was 1) to identify genes involved in the regulation of adrenal activity following ACTH stimulation and 2) to examine adrenal genes differentially expressed in individuals with high and low plasma corticosterone response following ACTH treatment.

Results

Analysis with 21 K poultry oligo microarrays indicated that ACTH treatment affected the expression of 134 genes. Several transcripts assigned to genes involved in the adrenal ACTH signaling pathway and steroidog

SUBMITTER: Bureau C 

PROVIDER: S-EPMC2751787 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature