Site-specific protein cross-linking with genetically incorporated 3,4-dihydroxy-L-phenylalanine.

ABSTRACT: Come together right now with L-DOPA: Chemical cross-linking is widely used to study protein-protein interactions. However, many cross-linking agents suffer from low reactivity or selectivity. An efficient and selective reaction of site-specific protein cross-linking was achieved using genetically incorporated 3,4-dihydroxy-L-phenylalanine.

SUBMITTER: Umeda A 

PROVIDER: S-EPMC2752657 | biostudies-literature | 2009 May

REPOSITORIES: biostudies-literature