Synthesis of (+)-CP-99,994 via Pd(0)-catalyzed asymmetric allylic and homoallylic C-H Diamination of terminal olefin.

ABSTRACT: This paper describes an asymmetric synthesis of the potent substance P receptor antagonist (+)-CP-99,994 from 4-phenyl-1-butene via Pd(0)-catalyzed asymmetric allylic and homoallylic C-H diamination.

SUBMITTER: Fu R 

PROVIDER: S-EPMC2752905 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature