Is prehypertension a risk factor for the development of type 2 diabetes?

ABSTRACT:

Objective

Prehypertension is associated with cardiovascular disease and insulin resistance. However, whether subjects with prehypertension have more diabetes risk is not known. We examine whether prehypertension is a risk factor for developing type 2 diabetes.

Research design and methods

Incident diabetes was examined in nondiabetic normotensive participants in the San Antonio Heart Study (n = 2,767; aged 25-65 years; median follow-up 7.8 years).

Results

Incident diabetes was 12.4% in subjects with prehypertension and 5.6% in subjects with normal blood pressure. The odds of incident diabetes were 2.21 greater for individuals with prehypertension than for those with normal blood pressure (95% CI 1.63-2.98) after adjusting for age, sex, and ethnicity. Prehypertension wa

SUBMITTER: Mullican DR 

PROVIDER: S-EPMC2752916 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature