Corey-Chaykovsky epoxidation of twisted amides: synthesis and reactivity of bridged spiro-epoxyamines.

ABSTRACT: The first example of a Corey-Chaykovsky epoxidation employing amides as substrates is described. Medium-bridged twisted amides serve as precursors to a family of isolable aminoepoxides. The reactivity of bridged spiro-epoxyamines is also investigated.

SUBMITTER: Szostak M 

PROVIDER: S-EPMC2753969 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature