Automated white-matter tractography using a probabilistic diffusion tensor atlas: Application to temporal lobe epilepsy.

ABSTRACT: Diffusion-weighted magnetic resonance imaging allows researchers and clinicians to identify individual white matter fiber tracts and map their trajectories. The reliability and interpretability of fiber-tracking procedures is improved when a priori anatomical information is used as a guide. We have developed an automated method for labeling white matter fiber tracts in individual subjects based on a probabilistic atlas of fiber tract locations and orientations. The probabilistic fiber atlas contains 23 fiber tracts and was constructed by manually identifying fiber tracts in 21 healthy controls and 21 patients with temporal lobe epilepsy (TLE). The manual tract identification method required approximately 40 h of manual editing by a trained image analyst using multiple regions of interest t

SUBMITTER: Hagler DJ 

PROVIDER: S-EPMC2754725 | biostudies-literature | 2009 May

REPOSITORIES: biostudies-literature