Functional consequence of plasmid DNA modified site-specifically with 7-deaza-deoxyadenosine at a single, programmable site.

ABSTRACT: Replacement of a single dA nucleotide positioned at a programmed site in a DNA plasmid with its 7-deaza-analog is described together with its complete resistance to restriction enzymatic cleavage.

SUBMITTER: Ang WH 

PROVIDER: S-EPMC2756714 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature