Trichosporon mycotoxinivorans, a novel respiratory pathogen in patients with cystic fibrosis.

ABSTRACT: This report describes the molecular epidemiology, in vitro susceptibility, colonial and microscopic morphologies, and biochemical features of Trichosporon mycotoxinivorans, a newly recognized pathogen that appears to have a propensity for patients with cystic fibrosis. The index patient died with histologically documented Trichosporon pneumonia complicating cystic fibrosis. This is also the first report of disease caused by a Trichosporon species in a nontransplant patient with cystic fibrosis. As T. mycotoxinivorans has not previously been recognized as a respiratory pathogen, the significance of its recovery from sputum samples was not initially appreciated. Genetic analysis of archived clinical samples found three additional cases of T. mycotoxinivorans infection which had previously be

SUBMITTER: Hickey PW 

PROVIDER: S-EPMC2756937 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature