The impact of combination antiretroviral therapy and its interruption on anxiety, stress, depression and quality of life in Thai patients.

ABSTRACT:

Objective

Investigation on anxiety, stress, depression, and quality of life (QoL) within STACCATO, a randomised trial of two treatment strategies: CD4 guided scheduled treatment interruption (STI) compared to continuous treatment (CT).

Participants

Thai patients with HIV-infection enrolled in the STACCATO trial.

Methods

Anxiety, depression assessed by the questionnaires Hospital Anxiety and Depression Scale (HADS) and DASS, stress assessed by the Depression Anxiety Stress Scale (DASS), and QoL evaluated by the HIV Medical Outcome Study (MOS-HIV) questionnaires. Answers to questionnaires were evaluated at 4 time-points: baseline, 24 weeks, 48 weeks and at the end of STACCATO.

Results

A total of 251 patients answered the HADS/DASS and 241 answered the MOS-HIV of

SUBMITTER: Nuesch R 

PROVIDER: S-EPMC2757643 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature