Spatiotemporal dynamics of low frequency fluctuations in BOLD fMRI of the rat.

ABSTRACT:

Purpose

To examine spatiotemporal dynamics of low frequency fluctuations in rat cortex.

Materials and methods

Gradient-echo echo-planar imaging images were acquired from anesthetized rats (repetition time = 100 ms). Power spectral analysis was performed to detect different frequency peaks. Functional connectivity maps were obtained for the frequency peaks of interest. The images in the filtered time-series were displayed as a movie to study spatiotemporal patterns in the data for frequency bands of interest.

Results

High temporal and spectral resolution allowed separation of primary components of physiological noise and visualization of spectral details. Two low frequency peaks with distinct characteristics were observed. Selective visualization of the second low freq

SUBMITTER: Majeed W 

PROVIDER: S-EPMC2758521 | biostudies-literature | 2009 Aug

REPOSITORIES: biostudies-literature