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Antibacterial cyclic D,L-alpha-glycopeptides.

ABSTRACT: We report the design, synthesis, membrane activity, biophysical characterization, and in vitro antibacterial activities of cationic cyclic D,L-alpha-glycopeptides bearing d-glucosamine (GlcNH(2)), D-galactose (Gal), or D-mannose (Man) glycosyl side chains.

SUBMITTER: Motiei L

PROVIDER: S-EPMC2758689 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature

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Antibacterial cyclic D,L-alpha-glycopeptides.

Motiei Leila L Rahimipour Shai S Thayer Desiree A DA Wong Chi-Huey CH Ghadiri M Reza MR

Chemical communications (Cambridge, England) 20090529 25

We report the design, synthesis, membrane activity, biophysical characterization, and in vitro antibacterial activities of cationic cyclic D,L-alpha-glycopeptides bearing d-glucosamine (GlcNH(2)), D-galactose (Gal), or D-mannose (Man) glycosyl side chains. ...[more]

PMID: 19557251

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