Neurobehavior disinhibition, parental substance use disorder, neighborhood quality and development of cannabis use disorder in boys.

ABSTRACT: This prospective investigation examined the contribution of neighborhood context and neurobehavior disinhibition to the association between substance use disorder (SUD) in parents and cannabis use disorder in their sons. It was hypothesized that both neighborhood context and son's neurobehavior disinhibition mediate this association. Two hundred and sixteen boys were tracked from ages 10-12 to age 22. The extent to which neighborhood context and neurobehavior disinhibition mediate the association between parental SUD and son's cannabis use disorder was evaluated using structural equation modeling. The best fitting model positioned neighborhood context and neurobehavior disinhibition as mediators of the association between parental SUD and cannabis use disorder in sons. Neurobehavior disinh

SUBMITTER: Ridenour TA 

PROVIDER: S-EPMC2759175 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature