Deficient activity in the neural systems that mediate self-regulatory control in bulimia nervosa.

ABSTRACT:

Context

Disturbances in neural systems that mediate voluntary self-regulatory processes may contribute to bulimia nervosa (BN) by releasing feeding behaviors from regulatory control.

Objective

To study the functional activity in neural circuits that subserve self-regulatory control in women with BN.

Design

We compared functional magnetic resonance imaging blood oxygenation level-dependent responses in patients with BN with healthy controls during performance of the Simon Spatial Incompatibility task.

Setting

University research institute.

Participants

Forty women: 20 patients with BN and 20 healthy control participants. Main Outcome Measure We used general linear modeling of Simon Spatial Incompatibility task-related activations to compare groups on thei

SUBMITTER: Marsh R 

PROVIDER: S-EPMC2759684 | biostudies-literature | 2009 Jan

REPOSITORIES: biostudies-literature