Does conduct disorder mediate the development of substance use disorders in adolescents with bipolar disorder? A case-control family study.

ABSTRACT:

Background

Recent work has highlighted important relationships among conduct disorder (CD), substance use disorders (SUD), and bipolar disorder in youth. However, because bipolar disorder and CD are frequently comorbid in the young, the impact of CD in mediating SUD in bipolar disorder youth remains unclear.

Method

105 adolescents with DSM-IV bipolar disorder (mean +/- SD age = 13.6 +/- 2.50 years) and 98 controls (mean +/- SD age = 13.7 +/- 2.10 years) were comprehensively assessed with a structured psychiatric diagnostic interview for psychopathology and SUD. The study was conducted from January 2000 through December 2004.

Results

Among bipolar disorder youth, those with CD were more likely to report cigarette smoking and/or SUD than youth without CD. However, CD pr

SUBMITTER: Wilens TE 

PROVIDER: S-EPMC2761736 | biostudies-literature | 2009 Feb

REPOSITORIES: biostudies-literature