MicroRNA expression profiling during the life cycle of the silkworm (Bombyx mori).

ABSTRACT:

Background

MicroRNAs (miRNAs) are expressed by a wide range of eukaryotic organisms, and function in diverse biological processes. Numerous miRNAs have been identified in Bombyx mori, but the temporal expression profiles of miRNAs corresponding to each stage transition over the entire life cycle of the silkworm remain to be established. To obtain a comprehensive overview of the correlation between miRNA expression and stage transitions, we performed a whole-life test and subsequent stage-by-stage examinations on nearly one hundred miRNAs in the silkworm.

Results

Our results show that miRNAs display a wide variety of expression profiles over the whole life of the silkworm, including continuous expression from embryo to adult (miR-184), up-regulation over the entire life cycle

SUBMITTER: Liu S 

PROVIDER: S-EPMC2761947 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature