Randomized trial on the effects of a 7-d low-glycemic diet and exercise intervention on insulin resistance in older obese humans.

ABSTRACT:

Background

The optimal combination of diet and exercise that produces the greatest reversal of obesity-related insulin resistance is unknown.

Objectives

We examined the effects of a combined 7-d low-glycemic index (low-GI) diet and exercise training intervention on insulin sensitivity in older obese humans.

Design

Participants [n = 32; mean (+/-SEM) age: 66 +/- 1 y; body mass index (in kg/m(2)): 33.8 +/- 0.7] were randomly assigned to a parallel, double-blind, controlled-feeding trial and underwent supervised aerobic exercise (EX; 60 min/d at 80-85% maximum heart rate) in combination with either a low-GI (LoGI + EX: 41.1 +/- 0.4) or a high-GI (HiGI + EX: 80.9 +/- 0.6) diet. All meals were provided and were isocaloric to individual energy requirements. Insulin sensitiv

SUBMITTER: Solomon TP 

PROVIDER: S-EPMC2762157 | biostudies-literature | 2009 Nov

REPOSITORIES: biostudies-literature