A computational predictor of human episodic memory based on a theta phase precession network.

ABSTRACT: In the rodent hippocampus, a phase precession phenomena of place cell firing with the local field potential (LFP) theta is called "theta phase precession" and is considered to contribute to memory formation with spike time dependent plasticity (STDP). On the other hand, in the primate hippocampus, the existence of theta phase precession is unclear. Our computational studies have demonstrated that theta phase precession dynamics could contribute to primate-hippocampal dependent memory formation, such as object-place association memory. In this paper, we evaluate human theta phase precession by using a theory-experiment combined analysis. Human memory recall of object-place associations was analyzed by an individual hippocampal network simulated by theta phase precession dynamics of human ey

SUBMITTER: Sato N 

PROVIDER: S-EPMC2762313 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature