Identification and characterization of miRNAs expressed in the bovine ovary.

ABSTRACT:

Background

MicroRNAs are the major class of gene-regulating molecules playing diverse roles through sequence complementarity to target mRNAs at post-transcriptional level. Tightly regulated expression and interaction of a multitude of genes for ovarian folliculogenesis could be regulated by these miRNAs. Identification of them is the first step towards understanding miRNA-guided gene regulation in different biological functions. Despite increasing efforts in miRNAs identification across various species and diverse tissue types, little is known about bovine ovarian miRNAs. Here, we report the identification and characterization of miRNAs expressed in the bovine ovary through cloning, expression analysis and target prediction.

Results

The miRNA library (5'-independent ligation

SUBMITTER: Hossain MM 

PROVIDER: S-EPMC2762473 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature