What do we know about the role of pharmacotherapy for smoking cessation before or during pregnancy?

ABSTRACT:

Significance

Given the substantial health risks of smoking during pregnancy, and the potential of pharmacotherapy to enhance quit rates, a need exists to examine the utility of pharmacotherapy for smoking cessation during pregnancy.

Literature review

We briefly review the first-line medications that are recommended for smoking cessation in nonpregnant adults. Additionally, we review the toxicity of tobacco smoke and the potential risks of pharmacotherapy as evidenced by animal studies. We review in more detail studies conducted in pregnant women, including (a) observational studies, (b) short-term safety and longer term uncontrolled studies, and (c) randomized controlled clinical trials (both effectiveness and efficacy studies).

Discussion

Because the safety and effic

SUBMITTER: Oncken CA 

PROVIDER: S-EPMC2762929 | biostudies-literature | 2009 Nov

REPOSITORIES: biostudies-literature