Layer-specific network oscillation and spatiotemporal receptive field in the visual cortex.

ABSTRACT: A quintessential feature of the neocortex is its laminar organization, and characterizing the activity patterns in different layers is an important step in understanding cortical processing. Using in vivo whole-cell recordings in rat visual cortex, we show that the temporal patterns of ongoing synaptic inputs to pyramidal neurons exhibit clear laminar specificity. Although low-frequency (approximately 2 Hz) activity is widely observed in layer 2/3 (L2/3), a narrow-band fast oscillation (10-15 Hz) is prominent in layer 5 (L5). This fast oscillation is carried exclusively by excitatory inputs. Moreover, the frequency of ongoing activity is strongly correlated with the spatiotemporal window of visual integration: Neurons with fast-oscillating spontaneous inputs exhibit transient visual respon

SUBMITTER: Sun W 

PROVIDER: S-EPMC2764922 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature