Risk stratification in critical limb ischemia: derivation and validation of a model to predict amputation-free survival using multicenter surgical outcomes data.

ABSTRACT:

Background

Patients with critical limb ischemia (CLI) are a heterogeneous population with respect to risk for mortality and limb loss, complicating clinical decision-making. Endovascular options, compared with bypass, offer a tradeoff between reduced procedural risk and inferior durability. Risk stratified data predictive of amputation-free survival (AFS) may improve clinical decision making and allow for better assessment of new technology in the CLI population.

Methods

This was a retrospective analysis of prospectively collected data from patients who underwent infrainguinal vein bypass surgery for CLI. Two datasets were used: the PREVENT III randomized trial (n = 1404) and a multicenter registry (n = 716) from three distinct vascular centers (two academic, one community-b

SUBMITTER: Schanzer A 

PROVIDER: S-EPMC2765219 | biostudies-literature | 2008 Dec

REPOSITORIES: biostudies-literature