Biosynthesis of the thiamin thiazole in Bacillus subtilis: identification of the product of the thiazole synthase-catalyzed reaction.

ABSTRACT: In this paper, we describe an optimized reconstitution of the thiamin thiazole synthase (ThiG) catalyzed reaction and demonstrate that the enzymatic product is an unanticipated dearomatized thiazole tautomer.

SUBMITTER: Hazra A 

PROVIDER: S-EPMC2765510 | biostudies-literature | 2009 Mar

REPOSITORIES: biostudies-literature