Identifying mild cognitive impairment at baseline in the Ginkgo Evaluation of Memory (GEM) study.

ABSTRACT:

Objectives

To identify, characterize and compare the frequency of mild cognitive impairment (MCI) subtypes at baseline in a large, late-life cohort (n = 3063) recruited into a dementia prevention trial.

Method

A retrospective, data-algorithmic approach was used to classify participants as cognitively normal or MCI with corresponding subtype (e.g. amnestic vs. non-amnestic, single domain vs. multiple domain) based on a comprehensive battery of neuropsychological test scores, with and without Clinical Dementia Rating (CDR) global score included in the algorithm.

Results

Overall, 15.7% of cases (n = 480) were classified as MCI. Amnestic MCI was characterized as unilateral memory impairment (i.e. only verbal or only visual memory impaired) or bilateral memory impairment (

SUBMITTER: Snitz BE 

PROVIDER: S-EPMC2767255 | biostudies-literature | 2009 Mar

REPOSITORIES: biostudies-literature